Scientists at the renowned University of Stanford are now showing a promising breakthrough as they were able to combat tumors and metastases by activating the body’s own immune cells with what they call ‘cancer vaccine’, as they announce in a statement.
The treatment was successful in 87 of 90 mice
To do this, researchers injected tiny amounts of two immunostimulating substances directly into cancerous tumors in mice. The activated T cells of the immune system not only destroyed the tumor itself but also other untreated metastases.
Treatment with the two drugs was successful in 87 out of 90 mice with lymphoma. The three mice that remained untreated were eventually cured with a second treatment.
Similar results were shown by the experiments in mice with melanoma as well as in mice with colon and breast cancer.
According to researchers, this shows that the substances have a healing effect on various cancers and hope for similar success in the treatment of humans.
Trials on humans with lymphoma started in January
The expectations of the two study leaders Ronald Levy and Idit Sagiv-Barfi are high.
Due to the precise administration and the low dose, the potential new cancer therapy would be quick and comparatively favorable. In addition, it would probably have fewer side effects than other immunotherapies.
In the meantime, the researchers expect the results of the trails on humans.
The study director is a pioneer of immunotherapy
Levy hopes to use the new method to minimize the disadvantages of traditional immunotherapy.
“Our approach is a one-time injection of tiny amounts of two substances that stimulate the immune cells only in the tumor itself. The mice showed great effects, including the elimination of all tumors in the body,” said Dr. Ronald Levy.
“When we administer the two substances together, we observe elimination of all tumors throughout the body,” adds Dr. Levy.
In conclusion, a cancer vaccine that works may be available really soon if shows the same effectiveness in humans as it did in lab mice.