Cannabidiol (CBD) Might Increase Ocular Pressure, New Study Showed

Cannabidiol (CBD) Might Increase Ocular Pressure, New Study Showed
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A new study carried out by scientists at Indiana University in the United States has demonstrated that cannabidiol (CBD), an essential chemical compound in medical marijuana, raises the pressure within the eyes.

This non-psychoactive cannabis substance is sold in a variety of products including oil, gummies, lotions, and nutritious foods. CBD has also been adopted in a number of countries, including Canada, as a therapy for medical disorders such as childhood epilepsy.

A recent study conducted on lab mice, issued in the journal Investigative Ophthalmology & Visual Science, has estimated that CBD resulted in an 18 percent rise in intraocular pressure within four hours following consumption. On the other hand, as previous researches have proven, tetrahydrocannabinol (THC) lowers ocular pressure.

The new research has uncovered that CBD is blocking this effect when combined with THC.

Cannabidiol (CBD) Might Increase Ocular Pressure, New Study Showed

In the trial, the male mice suffered a fall in eye pressure by approximately 30 percent within eight hours after THC consumption. Female mice experienced a similar effect but reduced.

The findings hint that women might be significantly less impacted by THC, even though the scientists aren’t sure if this applies to the substance’s psychoactive properties. “This difference between men and women, and the fact that CDB appears to worsen eye pressure, the main risk factor for glaucoma, are important aspects of this study. It is also remarkable that CDB appears to oppose the beneficial effects of THC actively,” the study’s authors explained.

“There were studies more than 45 years ago that found evidence that THC reduces pressure inside the eye, but no one has identified the specific neuroreceptors involved in the process until this study. These results may have important implications for future research on the use of cannabis as a therapy for intraocular pressure,” the scientists concluded.


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