Cancer Cells Turned Into Fat To Stop Cancer Development

Cancer Cells Turned Into Fat To Stop Cancer Development
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A scientific innovation that researchers succeeded in achieving is turning cancer cells into fat to stop the advancement of cancer. They succeeded in doing this by experimenting on lab mice. The researchers that conducted the experiments have published their findings in the journal Cancer Cell and appeared in January 2019.

The team of researchers inserted into mice an aggressive form of human breast cancer. After that, the scientists administered the rodents with two drugs, rosiglitazone, and trametinib. The first medication is a diabetic drug, while the second is used in treating cancer. Between the two drugs, trametinib was the one that really helped the cancer cells to turn into stem cells and the stem cells to turn into fat cells.

The other drug, rosiglitazone, only worked in collaboration with trametinib, helping it to counteract the dangerous cells more effectively. Together, they had a higher chance of constraining, dispersing, and stopping the evolution of cancer in mice than separate.

Cancer Cells Turned Into Fat To Stop Cancer Development

This process, of cancer cells transforming into fat, is named adipogenesis. While not all cancer cells had been converted into fat, the cells that did remain changed and did not multiply anymore. It is also important mentioning that the cancer cells in mice were actual human cancer cells and the fact that the treatment was so effective on then might mean that we have hope.

Good news is that the FDA approves both drugs. This means that scientist would be able to plan clinical trials for people to test the treatment in the future.

The researchers have already started examining if this treatment can work in combination with other cancer treatments, such as chemotherapy. Also, they want to find out if the drugs can have the same effect on different types of cancers.


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