New researchers are showing that an antibiotic mix has impacted the bacteria from the mice’s gut, and they have reached to a point where the growth and development of Alzheimer’s disease have been slowed in males. The University of Chicago, IL, has conducted the study, for the purpose to the demonstrate how could antibiotic taken for a long-term, may reduce the inflammation and can slow the growth in the male mice of the amyloid plaques.
What Are the Amyloid Plaques?
The Amyloid plaques are a characteristic of Alzheimer’s disease. The amyloid plaques are formed when a protein from the neurons of the brain is building up, and it’s forming clusters. The idea of the study has begun when the team of scientists has been studied the changes that appeared in the gut bacteria in people with Alzheimer. So, Professor S.Sisodia and his team have decided to make the study on mice for showing what the effects of the bacteria are and what the symptoms are.
However, the study has revealed that these changes to the limited development of amyloid plaques have happened only on the male mice, not on females. The team has used a mix of antibiotics to see how the amyloid plaques are affected and if the microglia are activated in the mice brains.
Antibiotics Might Help Alleviate Alzheimer’s Disease Symptoms
The immune cells (microglia) can cause inflammation in the brain when they are enabled.
Besides this, the researchers have found that the microbiome of the male is differently affected than the female mice. Unfortunately, for the female mice, the antibiotics are changing the gut bacteria. If this happens, the immune system will be affected, and this is increasing the activation of microglia.
Finally, the study was published in the Journal of Experimental Medicine, and the findings could help researchers to find a cure or a treatment that could stop the advancement of Alzheimer. Currently, some treatments are available, but they are helping only to manage the symptoms.