The ketogenic diet, often referred to as the “keto” diet, is a trendy high-fat, zero-carb method of eating that encourages weight reduction by forcing your metabolism to utilize fat instead of carbohydrates for energy. Despite promising research, the ketogenic diet is not recommended for cancer prevention or therapy by any major cancer group.
Whereas the ketogenic diet has numerous advantages, it also has significant drawbacks. For example, the diet is very heavy in fat. Furthermore, a variety of popular meals, like red meat, were related to an elevated risk of some cancers.
The diet is highly limited in regards of cancer-fighting nutrients including whole grains, fruit, and certain vegetables. It may also be challenging to consume enough calories when on a diet for folks who are receiving regular cancer therapies. Low-carb diets, like ketogenic diets, have been shown to aid weight loss.
Because of hormonal signaling that increases the growth of potentially malignant cells, a high-fat consumption in the diet is associated with an increased risk of colon cancer.
Link between keto diets and cancer
The research, which was conducted in a mouse model, found a relationship between lifestyle and genetics. According to the researchers, animals with an APC mutation, the most common genetic mutation seen in people with colon cancer, developed cancer quicker when given a high-fat diet. The intestine and colon (sometimes known as the “gut”) are very labor-intensive organs. Your gut must renew its lining on a regular basis when you eat to heal the harm done by digestive acids. The gut has a number of stem cells that may help to regenerate lining cells if needed.
As per experts, alterations in these stem cells are the most common cause of colorectal cancers. The APC gene, which controls cell division and operates as a “tumor suppressor,” is the most common colon cancer-linked mutation. This mechanism may be overridden by mutations in the APC gene, enabling cells to proliferate quickly and develop cancer.