Antibiotics Lead To Increased Risk Of Developing Serious Fungal Infection, As Per New Study

Antibiotics Lead To Increased Risk Of Developing Serious Fungal Infection, As Per New Study

Candidasis, a life-threatening fungal infection, is more common among patients given antibiotics in hospitals to avoid sepsis as well as other bacterial infections, according to recent research. Gut microbiomes are well known to have genetically programmed methods for surviving antibiotic exposure.

New research

Experts from the University of Birmingham in the UK, as well as the National Institutes of Health, conducted the study, which found that antibiotics interfere with the immune system within the intestines, allowing fungal infections to spread more easily. A further risk of bacterial infection was observed to exist in the areas where fungal infections originated because gut bacteria may escape.

Despite the fact that the research, released in Cell Host and Microbe, showed the prospect of immune-boosting medications, the scientists said their work also illustrates how antibiotics may have extra impacts on our systems that alter how we fight infection and illness. This, in turn, emphasizes the need of prudent use of the antibiotics that have been made accessible.

Antibiotic-treated mice were then infected with Candida albicans, which is the most prevalent fungus that generates invasive candidiasis in people, in this investigation. Even while infected mice were more likely to die, researchers determined that their higher mortality was due to an infection in their intestines, not their kidneys or any other organs.

Following this, the researchers looked for missing immune system components in the stomach of mice that had been treated with antibiotics and then employed human-style immune-boosting medicines to restore these components to the animals. Fungal infections were shown to be less severe after using this method.

This experiment was followed by a look at hospital records, where researchers found that identical co-infections may be present in persons who had been given antibiotics. By 2050, antibiotic-resistant diseases are expected to kill an estimated 1.2 million people globally, a figure that is expected to rise tenfold.

Anna Daniels

Anna is an avid blogger with an educational background in medicine and mental health. She is a generalist with many other interests including nutrition, women's health, astronomy and photography. In her free time from work and writing, Anna enjoys nature walks, reading, and listening to jazz and classical music.

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