The most common form of dementia, Alzheimer’s disease, varies by sex, and some biological clues were found by new research giving reasons why men are less likely to develop this condition than women. Men’s and women’s brains are different, so Alzheimer’s disease spreads according to what it finds. Scientists offered evidence concerning this issue at the Alzheimer’s Association International Conference in Los Angeles on Tuesday.
The association’s chief science officer, Maria Carrillo, said that just because women live longer, it does not mean that this is the reason why two-thirds of Alzheimer’s cases in the U.S. are found in women. She said that the sex differences in the disease are biologically underpinned. No matter at what age, men are less likely to develop Alzheimer’s than women, according to previous studies.
New research explained why Alzheimer’s disease affects more women than men
Regarding certain age groups, women have a higher risk of suffering from this disease compared to men because of the gene called APOE-4. The damage Alzheimers’s makes is easily masked by women without that being their purpose because they do better than men in verbal tests, so the early stages of this disease usually go undiagnosed.
Alzheimer’s disease variation in women and men has now more explanations and evidence of why that is happening thanks to new studies. A protein that forms tangles that destroy nerve cells, tau, spreads in the brain of a woman in a different way that it spreads in a man’s, according to the group of researchers from Vanderbilt University. About 300 people with healthy thinking skills were analyzed as well as 161 other people with mild impairment so experts could map the movements of tau. More areas of a woman’s brain are affected in comparison to men because tau networks in women with mild impairment spread and diffused more.