It’s just been revealed that there’s interesting news about gene therapy. Check out the latest reports below.
Gene therapy latest news is revealed
Gene therapy is able to alter a person’s genes in an attempt to cure disease. It’s important to note that this is different from traditional treatments because, rather than simply attempting to alleviate symptoms of an illness, this aims to fix the underlying cause of the disease.
How does gene therapy resolve the root cause of a medical illness? Viruses are the most commonly used gene therapy vectors. They have the natural ability to detect cells and transfer their genetic material or recombinant DNA into the genes of the cells. Scientists remove viruses’ disease-causing genes and replace them with the genes to stop the disease.
Polyethylene glycol (PEG) plays a crucial role in the successful medical application of gene therapy. This hydrophilic compound helps in the transfer of genetic material into competent cells. Scientists use PEG products from reputable sources to conduct intensive research on gene therapy.
Modifying biological molecules using PEG is known as PEGylation. It’s utilized as a way to reduce biopharmaceutical side effects. PEGylation involves attaching polymer PEG strands to molecules, including proteins, antibody fragments, and peptides, to boost the efficiency and safety of treatments. As a result, PEG-mediated transformation has higher survival rates for gene therapy treatments.
According to the notes that have been published in the original article, “The idea seemed theoretically enticing but was out of reach for many years, and it hit a major setback in 1999 when a teenager died in a clinical trial for gene therapy. However, further advances such as the 2012 discovery of CRISPR, a revolutionary technique for editing DNA, transformed gene therapy into a reality.”
Since then, the U.S. FDA has approved a number of gene therapies. They include treatments for several rare diseases, an inherited retinal disorder, relapsed or treatment-resistant leukemia and lymphoma, and, most recently, a form of hemophilia.
It’s also been revealed that clinical trial in Alzheimer’s involves a form of the disease caused by a specific genetic mutation.
“The treatment seeks to correct this flaw, which is present in roughly 2% of the population, by altering patients’ genetic makeup.” We suggest that you check out the complete article in order to learn more details.
Experimental CRISPR Technology Could Remove Detectable Cancer Cells
Accoridng to the latest reports, it seems that there is a groundbreaking treatment that has cleared a teenage girl’s incurable cancer.
Back in May 2022, 13-year-old Alyssa from Leicester became the first reported patient in the world to receive a new kind of CRISPR called base editing.
“The base-edited T-cells at Great Ormand Street Hospital for Children (GOSH), in collaboration with the UCL Great Ormond Street Institute of Child Health (UCL GOS ICH), treated Alyssa’s “incurable” T cell leukemia, leaving her with zero detectable cancer cells,” a press release reported.
Check out the previous article in order to learn more details.