A research found that persons with obesity who took a diabetes medicine lost significant amounts of weight. Experts believe that a weekly injection of tirzepatide might have a profound impact on the game. Experts have lauded this as a “game-changing” advance in the treatment of obesity, which involves taking a diabetic medicine once a week.
According to the WHO, obesity is responsible for 1.2 million deaths per year throughout Europe, with the UK having one of the highest rates. Diet and exercise have long been the focus of efforts to combat the condition, but many individuals who lose weight this way eventually gain it back. Obese patients may benefit from using a diabetic medicine in conjunction with other treatment options. Trial participants dropped up to 20% of their body weight in only 72 weeks.
The New England Journal of Medicine published an international team’s findings that they randomly divided 2,539 obese or overweight people into four equal subgroups.
While the other three groups received either 5mg, 10mg or 15mg of a medication called tirzepatide one time a week for 72 weeks, one group received a self-administered placebo shot. All individuals also received weekly sessions of lifestyle counseling to assist them in maintaining a diet low in calories and a weekly exercise regimen of at least 150 minutes. Participants’ average weight was 104.8 kilograms, or 16.5 stone, and 94.5 percent of them were classified as obese. As far as researchers know, none of them had diabetes.
The results
Nearly 82% of the sample adhered to the assigned treatment, which resulted in an average weight loss of 16.1 kilograms, 22.2 kilograms, and 23.6 kilograms, respectively, at the conclusion of the 72-week study period, according to the data. They dropped an average of 2.4 kg among those who received a placebo injection
According to the researchers, 91% of those who received the maximum dosage of tirzepatide lost 5% or more of their body weight, comparing to just 35% of those who received the placebo. When given the greatest dosage, 57% of those given the placebo dropped 20% of their weight, compared to only 3% of those given the highest dose of the medication.
